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  • Leon Apel 3:16 pm on July 30, 2015 Permalink | Reply  

    ART WILLIAMS JUST DO IT 

    “The most important thing you need to win in business…is a very unique kind of mental toughness. I believe the difference in winning and losing in the free enterprise system is so small it’s almost too scary to talk about. You can do 99% of the things right in business right yet if you don’t possess that winning edge, that mental toughness folks, it’s impossible to win.”

    Listen to https://www.youtube.com/watch?v=7R9c0RAz678 from 4:00 to 4:30

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  • Leon Apel 11:10 pm on July 26, 2015 Permalink | Reply  

    Applying Artificial Intelligence to Solve Problems 

    We have amazing technology capable of organizing data, predicting behavior and reasoning. I think the potential applications of this behavior will inevitably change how humans interact with the world.

    With around seven billion people on the planet, there’s at least 99% chance that another human being is better than you and I at almost every physical, or intellectual task.

    It’s logical then that humans should allow those with the best reasoning skills to solve the world’s most challenging problems.

    Instead of spending hours and guesstimating an optimal outcome, I think humans should immediately insist on applying artificial intelligence to make optimal decisions.

    Especially since some problems involve multiple levels of reasoning, and combining many data sets, I think it’s essential to apply artificial intelligence technology like IBM Watson to solve the world’s biggest problems.

    Artificial intelligence can help humans speed up the pace of innovation and come up with more optimized outcomes.

    Some sample applications include the following:

    • Weather Management: Deciding objectively with global warming or global cooling is taking place. Learning which factors are contributing the most to global cooling/warming and ensuring the world stays balanced
    • Energy: Solving energy problems by having a computer figure out the best way to optimize and integrate renewable energy resources
    • Biotechnology/Health Care: Helping humans stay healthier
    • Food and water management/nutrition: Deciding on the best ways to keep people healthy and manage food and water supplies.
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  • Leon Apel 4:16 pm on July 18, 2015 Permalink | Reply  

    Metformin improves healthspan and lifespan in mice. 

    According to https://blogs.ucl.ac.uk/gee-research/tag/nematode/ “The anti-ageing properties of Metformin appear to be two-fold. By activating AMPK, Metformin may mediate life extension through its influences on key signalling pathways, essentially mimicking dietary restriction. Secondly, Metformin alters folate metabolism in microbial symbionts, reducing methionine production and again mimicking a restricted diet. Importantly, in the absence of the gut microbes, the drug showed strongly toxic effects, indicating that in some way, E.coli is able to ameliorate the drug’s toxicity. The effect of the drug Metformin is the result of a complex interplay between both toxic and beneficial effects on the host and the gut microbiota. Finally, all of this appears to interact with the diet of the nematode – feeding nematodes on a high-sugar diet eliminated the positive effects of Metformin.”

    According to http://www.ncbi.nlm.nih.gov/pubmed/23900241 “At a molecular level, metformin increases AMP-activated protein kinase activity and increases antioxidant protection, resulting in reductions in both oxidative damage accumulation and chronic inflammation.”

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  • Leon Apel 7:24 pm on July 14, 2015 Permalink | Reply  

    Biotechnology Investors 

    If you would like to apply for my syndicate to fund ventures focused on biotechnology in the fields of disease identification/prevention, regenerative medicine, nutrition and longevity please complete the Google form below. Note: You will only be contacted if a deal meets your criteria. You will not be solicited for other purposes. You must be an accredited investor.

    Click Here to Apply for my Biotechnology Syndicate

    Disclaimer: This is not a public offering. This is simply a private group interested in collaborating in funding biotechnology ventures. You understand that you are solely responsible for reviewing any fund, its offering and any statements made by a fund or its manager and for performing such due diligence as you may deem appropriate, including consulting your own legal and tax advisers, and that any information provided by us shall not form the primary basis of your investment decision.

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  • Leon Apel 4:09 pm on July 14, 2015 Permalink | Reply  

    “Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population” 

    http://www.cell.com/cell-metabolism/abstract/S1550-4131(14)00062-X

    “We studied simple organisms, mice, and humans and provide convincing evidence that a high-protein diet — particularly if the proteins are derived from animals — is nearly as bad as smoking for your health,” said the Dr. Valter Longo, Professor of Gerontology/Alzheimer’s Research/Cancer Research, Biological Sciences at the University of Southern California, who is the senior author of one of the papers.

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