Monthly Archives: June 2016

Potential CRISPR Healthspan applications

Potential CRISPR Healthspan applications: TFAM (Transcription Factor A, Mitochondrial) – gene engineering allows cells to manufacture a nicotinamide mononucleotide (NMN) precursor on their own Allows “overall rejuvenation, including reversal of signs of muscle atrophy, inflammation, and insulin resistance” GDF11 (growth differentiation factor 11) – GDF11 has been reported to rejuvenate the heart, muscles, and brain: “GDF11 has been reported… Read More »

4 Pathways to Reverse Damage/Aging

Use Telomerase activators: “Drugs that turn on our own telomerase (using the HTERT gene) and thereby reset gene expression.” Use Telomerase Protein “Use messenger RNA for telomerase (accomplished by Helen Blau’s group at Stanford)” “Deliver telomerase gene itself (either via liposomes or viral vectors) to the body’s cells” Several groups are doing this include Telocyte.  Telocyte… Read More »