Only 8% Success Rate of Animal to Human Clinical Trials

According to http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902221/

“The average rate of successful translation from animal models to clinical cancer trials is less than 8%. Animal models are limited in their ability to mimic the extremely complex process of human carcinogenesis, physiology and progression. Therefore the safety and efficacy identified in animal studies is generally not translated to human trials.”

Rapamycin may alter the aging process

“The most promising treatment right now is a mysterious drug called Rapamycin.

Dr. Dean Kellogg, a UT Medicine and Barshop Institute researcher and clinical doctor working at the San Antonio Veterans Affairs, says he’s been testing the drug on eight people in the San Antonio area.”

“I never really thought I would see a pharmacological agent that can alter the aging process,” said Kellogg. “Rapamycin appears to slow the aging process.”

“Kellogg says the pill works by mimicking the effects of a low-calorie diet, tricking a cellular mechanism that regulates cell growth and consumption of nutrients. It forces cells into a conservative state, preventing the tiny factories from overworking and causing wear and tear.”

Article source: http://www.khou.com/story/news/health/2015/07/27/fountain-of-youth-texas-scientists-testing-breakthrough-aging-drug/30723181/